The effect of ticagrelor and clopidogrel on angiographic parameters according to diabetic status in patients with ST elevation myocardial infarction

Aim . We aimed to compare post-interventional angiographic outcomes of ticagrelor versus clopidogrel according glycosylated hemoglobin (HbA1c) levels in patients with ST-elevation myocardial infarction. Material and methods The study included a total 532 patients, 334 receiving (62,8%) 198 (37,2%). Diabetic status the was assessed HbA1c. TIMI flow grade frame count were calculated compared between two groups. Results 3 higher TFC lower after percutaneous coronary intervention infarct-related artery treated (89,2% vs. 73,7%; p< 0,001, 20 24; 0,001). There positive correlation increases HbA1c whole group (r=0,225; p=0,004). In subgroup analysis, did not affect using (r=-0,060; p=0,326 for noreflow, r=-0,133; p=0,321 TIMI-3 flow). While level flow, presence post-procedural no-reflow caused worsening as increased (r=0,374; p=0,005). Conclusion Ticagrelor found be better terms parameters regardless diabetes.